Frontiers in Neuroscience | Neuropharmacology

Clinical Trial

Published on 02 May 2025

An exploratory analysis of bezisterim treatment associated with decreased biological age acceleration, and improved clinical measure and biomarker changes in mild-to-moderate probable Alzheimer's disease

in Neuropharmacology

Christopher L. Reading
Jiayan Yan
Marcia A. Testa
Donald C. Simonson
Hira Javaid
Lisa Schmunk
Daniel E. Martin-Herranz
Robert Brooke
Juozas Gordevicius
Jeffrey Zhang

Frontiers in Neuroscience

doi 10.3389/fnins.2025.1516746

179 views

Original Research

Accepted on 30 Apr 2025

Preliminary study on the time-correlation changes in brain neurotransmitters of mice exposed to mushroom toxin ibotenic acid

in Neuropharmacology

Ruanxian Dai
Zhantao Duan
Bin Han
Guobing Chen
Fuping Wang
Zhuange Shi
Xian Zhou
Haifei Song
Li Ma
Qiang Meng

Frontiers in Neuroscience

doi 10.3389/fnins.2025.1561291

Original Research

Accepted on 24 Apr 2025

Collagen Mimetic Peptides as Novel Therapeutics for Vascular Disease in the Central Nervous System

in Neuropharmacology

Olivia L Bossardet
Joseph M Holden
Brian J Del Buono
Eric Schlumpf
Lauren K Wareham
David J Calkins

Frontiers in Neuroscience

doi 10.3389/fnins.2025.1569347

208 views

Original Research

Accepted on 17 Apr 2025

9 Patients Report Seizure Freedom with Medical Cannabis Treatment for Drug-Resistant Epilepsy: A Case Series

in Neuropharmacology

Frank Yizhao Chen
Joshua Myles Duckman
Brenden Samuel Rabinovitch
Katrin Julia Hannesson
Evan Cole Lewis

Frontiers in Neuroscience

doi 10.3389/fnins.2025.1570531

335 views

Review

Accepted on 15 Apr 2025

Behavioral Manifestations and Underlying Mechanisms of Amphetamine in Constructing Animal Models of Mania: A Comprehensive Review

in Neuropharmacology

Zi-Qi Deng
Xiao-Chen Si
Jia-Bin Song
Jin-Yao Li
Lu Sun
Xue Dang
Yanchen Feng
Yanchen Feng
Feixiang Liu

Frontiers in Neuroscience

doi 10.3389/fnins.2025.1544311

129 views

Original Research

Published on 04 Apr 2025

Purinergic receptor antagonism reduces interictal discharges and rescues cognitive function in a mouse model of temporal lobe epilepsy

in Neuropharmacology

Nelson Espinosa
Soraya Martín-Suárez
Ariel Lara-Vasquez
Trinidad Montero
Teresa Muro-García
German Fernandez
Juan Manuel Encinas-Pérez
Pablo Fuentealba

Frontiers in Neuroscience

doi 10.3389/fnins.2025.1513135

786 views

Original Research

Published on 01 Apr 2025

Abnormal response to chronic social defeat stress and fear extinction in a mouse model of Lynx2-based cholinergic dysregulation

in Neuropharmacology

Kristin R. Anderson
Peter J. Rogu
Talulla B. Palumbo
Julie M. Miwa

Frontiers in Neuroscience

doi 10.3389/fnins.2025.1466166

961 views

Review

Published on 19 Mar 2025

Ferroptosis-associated signaling pathways and therapeutic approaches in depression

in Neuropharmacology

Xuyang Feng
Wenyu Zhang
Xiaoxi Liu
Qiuxuan Wang
Xiao Dang
Jingxian Han
Xuezhu Zhang

Frontiers in Neuroscience

doi 10.3389/fnins.2025.1559597

869 views

Mini Review

Published on 18 Mar 2025

Effect and mechanism of GLP-1 on cognitive function in diabetes mellitus

in Neuropharmacology

Xiaoke Dou
Lei Zhao
Jing Li
Yaqiu Jiang

Frontiers in Neuroscience

doi 10.3389/fnins.2025.1537898

1,449 views

Systematic Review

Published on 07 Mar 2025

Effects of neostigmine on postoperative neurocognitive dysfunction: a systematic review and meta-analysis

in Neuropharmacology

Xuelei Zhou
Linlin Chen
Li Zhao
Wei Mao
Xianchun Liu
Longyi Zhang
Ying Xie
Linji Li

Frontiers in Neuroscience

doi 10.3389/fnins.2025.1464272

817 views

Brief Research Report

Published on 27 Feb 2025

Decoding tinnitus progression: neurochemical shifts in the anterior cingulate cortex revealed by magnetic resonance spectroscopy

in Neuropharmacology

Mengfang Gong
Shuting Han
Yongcong Shen
Yonggang Li
Ji-Sheng Liu
Duo-Duo Tao

Frontiers in Neuroscience

doi 10.3389/fnins.2025.1551106

1,722 views

Original Research

Published on 26 Feb 2025

Chronic unpredictable mild stress induces anxiety-like behavior in female C57BL/6N mice, accompanied by alterations in inflammation and the kynurenine pathway of tryptophan metabolism

in Neuropharmacology

Yanqin Luo
Ning Jiang
Yiwen Zhang
Yongzhi Zhao
Fang Chen
Xueyan Li
Meng Qiang
Guirong Zeng
Qinghu He
Xinmin Liu

Frontiers in Neuroscience

doi 10.3389/fnins.2025.1556744

1,363 views

Review

Published on 19 Feb 2025

Clinical efficacy and potential mechanisms of acupuncture for Parkinson’s disease: the role of GABAergic signaling

in Neuropharmacology

Wenhui Lu
Ting Zhang
Minghui Li
Jun Zhang
Ningning Liu
Lanfang Yang
Guomin Huang

Frontiers in Neuroscience

doi 10.3389/fnins.2025.1525486

1,276 views
1 citation

Editorial

Published on 19 Feb 2025

Editorial: Therapeutic potential of cannabinoids: from health to disease

in Neuropharmacology

Évila Lopes Salles
Babak Baban
Xu Qin
Valdemar Paffaro

Frontiers in Neuroscience

doi 10.3389/fnins.2025.1565790

769 views

Original Research

Published on 18 Feb 2025

Dezocine modulates the reinstatement of conditioned place preference in morphine-dependent rats via the dopamine reward circuitry

in Neuropharmacology

Yan He
Zhi-Sheng Piao
Yi Jia
Hui-Qi Wu
Xiao-Qiang Wang
Wei-Feng Yu
Fei-Xiang Wu

Frontiers in Neuroscience

doi 10.3389/fnins.2025.1507747

768 views

Correction

Published on 17 Feb 2025

Corrigendum: D-serine contributes to seizure development via ERK signaling

in Neuropharmacology

Tie Ma
Yin Wu
Beibei Chen
Wenjuan Zhang
Lang Jin
Chenxi Shen
Yazhou Wang
Yonghong Liu

Frontiers in Neuroscience

doi 10.3389/fnins.2025.1541189

445 views