Frontiers in Genetics

Original Research

Published on 02 May 2025

Impact of different genomic relationship matrix construction methods on the accuracy of genomic prediction in different species

Shiyi Wang
Yingjia Wei
Dengying Liu
Xiangzhe Zhang
Qishan Wang
Yuchun Pan
Peipei Ma

Frontiers in Genetics

doi 10.3389/fgene.2025.1576248

150 views

Review

Published on 02 May 2025

Integrative genetic and epigenetic control of skeletal muscle fiber traits in agricultural animals

Xiaolong Chang
Junwu Ma

Frontiers in Genetics

doi 10.3389/fgene.2025.1566553

Original Research

Published on 02 May 2025

Validation of a comprehensive long-read sequencing platform for broad clinical genetic diagnosis

Siddhartha Sen
Hillary P. Handler
Alec Victorsen
Zach Flaten
Aidan Ellison
Todd P. Knutson
Sarah A. Munro
Ryan J. Martinez
Charles John Billington
Jennifer J. Laffin

Frontiers in Genetics

doi 10.3389/fgene.2025.1499456

240 views

Technology and Code

Published on 02 May 2025

TCGADownloadHelper: simplifying TCGA data extraction and preprocessing

Alexandra Anke Baumann
Olaf Wolkenhauer
Markus Wolfien

Frontiers in Genetics

doi 10.3389/fgene.2025.1569290

Original Research

Published on 02 May 2025

RNA hybrid-capture next-generation sequencing has high sensitivity in identifying known and less characterized oncogenic and likely oncogenic NTRK fusions in a real-world standard-of-care setting

Zachary D. Wallen
Marni Tierno
Erica Schnettler
Alison Roos
Michelle Green
Kobina Amoah
Rebecca A. Previs
Stephanie Hastings
Sarabjot Pabla
Taylor J. Jensen

Frontiers in Genetics

doi 10.3389/fgene.2025.1550706

105 views

Review

Published on 01 May 2025

In vitro 3D modeling of colorectal cancer: the pivotal role of the extracellular matrix, stroma and immune modulation

Veroniaina Hanitrarimalala
Zdenka Prgomet
My Hedhammar
Helena Tassidis
Anette Gjörloff Wingren

Frontiers in Genetics

doi 10.3389/fgene.2025.1545017

199 views

Original Research

Published on 01 May 2025

Development and validation of a polygenic risk score for height in a Greek cohort: Association with blood pressure measurements

Ioanna Panagiota Kalafati
Margaritis Tsifintaris
Maria Dimitriou
Effimia Grigoriou
Panagiotis Moulos
George V. Dedoussis

Frontiers in Genetics

doi 10.3389/fgene.2025.1538975

174 views

Original Research

Published on 01 May 2025

Radiomic features and tumor immune microenvironment associated with anaplastic lymphoma kinase-rearranged lung adenocarcinoma and their prognostic value

Ying Han
Wenya Feng
Huaxin Li
Hua Wang
Zhaoxiang Ye

Frontiers in Genetics

doi 10.3389/fgene.2025.1581937

206 views

Original Research

Published on 01 May 2025

Identification of potential crucial genes and mechanisms associated with metabolically unhealthy obesity based on the gene expression profile

Qingqing Wang
Silu Wang
Zhanyu Zhuang
Xueting Wu
Hongkun Gao
Tianyi Zhang
Guorong Zou
Xing Ge
Yapeng Liu

Frontiers in Genetics

doi 10.3389/fgene.2025.1540721

186 views

Brief Research Report

Accepted on 30 Apr 2025

Allelic dropout in the endoglin (ENG) gene caused by common duplication beyond the primer binding site

Anna Shestak
Victoria Rumyantseva
Elena Zaklyazminskaya

Frontiers in Genetics

doi 10.3389/fgene.2025.1571437

Original Research

Accepted on 30 Apr 2025

Integrative transcriptomics and single-cell transcriptomics analysis reveal potential biomarkers and mechanisms of action in papillary thyroid carcinoma

WanChen Cao
Kai Gao
Yi Zhao

Frontiers in Genetics

doi 10.3389/fgene.2025.1536198

Opinion

Accepted on 30 Apr 2025

From Bites to Bytes: Understanding How and Why Individual Malaria Risk Varies Using Artificial Intelligence and Causal Inference

Adèle Helena Ribeiro
Julia Pavan Soler
Rodrigo M Corder
Marcelo Ferreira
Dominik Heider

Frontiers in Genetics

doi 10.3389/fgene.2025.1599826

Correction

Accepted on 30 Apr 2025

Application of rapid clinical exome sequencing technology in the diagnosis of critically ill pediatric patients with suspected genetic diseases

Xuejun Ouyang
Dazhi Chi
Yu Zhang
Tian Yu
Qian Zhang
Lei Xu
Victor, Wei Zhang
Bin Wang

Frontiers in Genetics

doi 10.3389/fgene.2025.1620297

Original Research

Accepted on 30 Apr 2025

EGFR Polymorphisms Drive Lung Cancer Risk and Survival Disparities: A Genotype-Expression-Outcome Cohort Study

Chao Zuo
Ziqiang Wang
Yi Liu
Jing Cheng
Dongli Yang
Yu Wang
Yong-chao Qiao

Frontiers in Genetics

doi 10.3389/fgene.2025.1591539

Original Research

Accepted on 30 Apr 2025

IGF-1 secreted by Mesenchymal Stem Cells affects the function of Lymphatic Endothelial Progenitor Cells: A potential strategy for the treatment of lymphedema

Zekuan Xue
Dongdong Yang
Zhiwei Jin
Yijie Li
Yunfei Yu
Xinchun Zhao
Yongzhou Huang
Shengqiu Jia
Tong Zhang
Guilin Huang

Frontiers in Genetics

doi 10.3389/fgene.2025.1584095

Original Research

Published on 30 Apr 2025

Impact of nonsynonymous single nucleotide polymorphisms in PROCR gene on protein stability and thrombotic risk: a molecular dynamic approach

Hytham Ahmed Abuagla
Khalid Mohamed Adam
Mohamed E. Elangeeb
Elsadig Mohamed Ahmed
Elshazali W. Ali
Ali M. Edris
Abubakr Ali Elamin MohamedAhmed
Elmoiz Idris Eltieb
Tarig Babikir Algak Khalid
Bahaeldin K. Elamin

Frontiers in Genetics

doi 10.3389/fgene.2025.1580993

294 views